Polypeptides are formed by which type of reaction?

• A. Hydrolysis
• B. Oxidation
• C. Condensation reactions
• D. Isomerization

Answer: (C)

Polypeptide formation happens through condensation (dehydration synthesis) reactions. When two amino acids come together, the amino group of one reacts with the carboxyl group of the other, releasing a water molecule and forming a peptide bond. Repeating this linkage builds long polypeptide chains.

This is the mechanism that creates the polymer backbone, whereas hydrolysis would break polypeptides by adding water, not form them. Oxidation involves electron transfer and isn’t how amino acids link, and isomerization is just rearranging atoms within a molecule, not forming the peptide bonds that connect amino acids.